| The research focuses on the secretory mechanism
and pathophysiological actions of mast cells. Diseases investigated
include: atopic dermatitis, arthritis, autism, coronary artery inflammation,
interstitial cystitis, migraines and multiple sclerosis. These diseases
worsen by stress and we have identified that mast cells both contain
and respond to stress hormones. The techniques used include molecular
biology, cell biology, and various microscopic techniques, as well
as animal models for the target diseases in which mast cells are involved. |
